When less may not be best-The challenge of individualising antiviral therapy for chronic hepatitis C infection
نویسندگان
چکیده
منابع مشابه
indefinite antiviral therapy may be required after surgical resection for hepatocellular carcinoma complicating chronic hepatitis b
this report describes a 66-year-old male who had a long history of hepatitis b virus (hbv) infection. he was found hepatocellular carcinoma (hcc) 5 months after lamivudine resistance mutation and then received a successful hepatectomy. three years later, hepatitis b envelope antigen seroconversion was achieved and nucleoside analogs were discontinued. after the withdrawn of antiviral treatment,...
متن کاملSerum vaspin may be a good indicator of fibrosis in chronic hepatitis C and is not altered by antiviral therapy.
Vaspin was found to modulate insulin resistance (IR) and to inhibit proinflammatory and profibrogenic agents. The aim of the study was to evaluate vaspin serum concentration prior to and after antiviral treatment and to assess its relationship with morphological alterations, IR and response to antiviral therapy. The study encompassed 75 non-obese, non-diabetic chronic hepatitis C (CHC) patient...
متن کاملIndefinite antiviral therapy may be required after surgical resection for hepatocellular carcinoma complicating chronic hepatitis B
This report describes a 66-year-old male who had a long history of hepatitis B virus (HBV) infection. He was found hepatocellular carcinoma (HCC) 5 months after lamivudine resistance mutation and then received a successful hepatectomy. Three years later, hepatitis B envelope antigen seroconversion was achieved and nucleoside analogs were discontinued. After the withdrawn of antiviral treatment,...
متن کاملDirect-acting antiviral medications for chronic hepatitis C virus infection.
Treatment of hepatitis C virus has traditionally been difficult because of low rates of treatment success and high rates of treatment discontinuation due to side effects. Current standard therapy consists of pegylated interferon α and ribavirin, both of which have nonspecific and largely unknown mechanisms of action. New therapies are in development that act directly on the hepatitis C virus at...
متن کاملoccult hepatitis b virus infection in patients with chronic hepatitis c treated with antiviral therapy
background occult hepatitis b virus infection (obi) is defined as the presence of hepatitis b virus (hbv) dna in the liver and/or in the serum of patients with negative results of hepatitis b s antigen (hbsag) test with or without serological markers of previous viral exposure. the impact of obi in patients with chronic hepatitis c (chc) is still unclear. objectives the aim of this study was to...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology and Hepatology
سال: 2009
ISSN: 0815-9319,1440-1746
DOI: 10.1111/j.1440-1746.2009.05788.x